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原賢康 Masayasu Hara

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Nickname
原賢康 Masayasu Hara
Self introduction
講師 Lecturer

専門 下部消化管 大腸癌治療
    大腸癌腹腔鏡手術
    大腸癌における低侵襲手術
    大腸癌に対する新規分子標的治療の研究
大腸癌進展と炎症(IL-6)との関連

所属学会 
日本外科学会 専門医
日本臨床外科学会
日本消化器外科学会 専門医
日本大腸肛門病学会 専門医
日本癌学会
日本内視鏡外科学会
日本静脈経腸栄養学会
がん治療認定医

2012.3~2013.2 Korea University(Seoul)にて腹腔鏡手術、ロボット手術を研修

業績
1. Hara M
Isolated tumor cell in lateral lymph node has no influences on the prognosis of rectal cancer patients. Int J Colorectal Dis 2007; 22(8):911-7.

2. Hara M
Comparative analysis of intraperitoneal minimal free cancer cells between colorectal and gastric cancer patients using quantitative RT-PCR: possible reason for rare peritoneal recurrence in colorectal cancer. Clin Exp Metastasis 2007; 24(3):179-89.

3. Hara M
Negative serum carcinoembryonic antigen has insufficient accuracy for excluding recurrence from patients with Dukes C colorectal cancer: analysis with likelihood ratio and posttest probability in a follow-up study. Dis Colon Rectum 2008; 51(11):1675-80.

4. Hara M
Interleukin-2 potentiation of cetuximab antitumor activity for epidermal growth factor receptor-overexpressing gastric cancer xenografts through antibody-dependent cellular cytotoxicity. Cancer Sci 2008; 99(7):1471-8.

5. Hara M
Angle between 1 and 4 min gives the most significant difference in time-intensity curves between benign disease and breast cancer: analysis of dynamic magnetic resonance imaging in 103 patients with breast lesions.
Clin Imaging. 2009 Sep-Oct;33(5):335-42.

6. Hara M
Does serum carcinoembryonic antigen elevation in patients with postoperative stage II colorectal cancer indicate recurrence? Comparison with stage III.
J Surg Oncol. 2010 Aug 1;102(2):154-7.

7. Hara M
Percutaneous endoscopic gastrojejunostomy for a patient with an intractable small bowel injury after repeat surgeries: a case report.
J Med Case Reports. 2011 Feb 10;5(1):55.

8. Hara M
Single-port retrieval of peritoneal foreign body using SILS port: report of a case.
Surg Laparosc Endosc Percutan Tech. 2011 Jun;21(3):e126-9.

9. Hara M
Accuracy of monitoring serum carcinoembryonic antigen levels in postoperative stage III colorectal cancer patients is limited to only the first postoperative year.
Surg Today. 2011 Oct;41(10):1357-62. 2011 Sep 16.

10. Hara M
Laparoscopic Anterior Resection for Colorectal Cancer without Mini-Laparotomy Utilizing Trans-Anal Bowel Reversing Retrieval Surg Laparosc Endosc Percutan Tech.2011.10(21)e235–e238

11. Hara M
Curatively Resected Isolated Inguinal Lymph Node Metastasis from Cecum Cancer: Report of a Case
Surg Today.

12. Hara M
Transvaginal Resection of a Rectal Gastrointestinal Stromal Tumor: Report of a Case. Surg Today.

13. Hara M
Laparoscopic Intersphincteric Resection with SILS Port for Very Low Rectal Cancer
Surg Laparosc Endosc Percutan Tech

14.Sng KK, Hara M,
The multiphasic learning curve for robot-assisted rectal surgery.
Surg Endosc. 2013 Sep;27(9):3297-307. Epub 2013 Mar 19.

15. Hara M
Carcinoembryonic antigen elevation in posthepatectomy patients with colorectal cancer liver metastasis indicates recurrence with high accuracy.
Hepatogastroenterology, peer reviewed, 2013, in press

16. Hara M
The herbal drug, polysaccharide K, has an immunological and synergistic anticancer effect with cetuximab for gastrointestinal cancer in vivo.
GJMR, peer reviewed, 2013, in press

17.Nagasaki T, Hara M,
Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour-stroma interaction.
Br J Cancer. 2014 Jan 21;110(2):469-78

18.T Nagasaki, M Hara,et al
Relationship between inflammation and cancer progression: review of the recent advances in interleukin-6 signaling and its blockage in cancer therapy Receptors & Clinical Investtigation

19 M Hara
Robotic-Assisted Surgery for Rectal
Adenocarcinoma: Short-term and Midterm Outcomes From 200 Consecutive Cases at a Single Institution
2014 Dis Col & Rec 57:570-577
ゲストブック
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